Human Papillomavirus Type 16 Variant Analysis of E 6 , E 7 , L 1 1 Genes and Long Control Region in Cervical Carcinomas from 2 Patients in Northeast China
نویسندگان
چکیده
19 Human papillomaviruses type 16 (HPV 16) plays a cardinal role in the pathogenesis of 20 cervical cancer. HPV 16 has intratypic variants which show different geographical distribution 21 and different oncogenic potential. To analyze the presence of sequence variations of HPV 16 22 Copyright © 2011, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Clin. Microbiol. doi:10.1128/JCM.02203-10 JCM Accepts, published online ahead of print on 18 May 2011 on N ovem er 3, 2017 by gest ht://jcm .sm .rg/ D ow nladed fom on N ovem er 3, 2017 by gest ht://jcm .sm .rg/ D ow nladed fom on N ovem er 3, 2017 by gest ht://jcm .sm .rg/ D ow nladed fom
منابع مشابه
Human Papillomavirus Type 16 Variant Analysis of E6, E7, and L1 Genes and Long Control Region in Identification of Cervical Carcinomas in Patients in Northeast China
Department of Microbiology, Harbin Medical University, Heilongjiang Key Laboratory of Infection and Immunity, Heilongjiang Province, and Pathogenic-Biological Key Laboratory, Heilongjiang Higher Education Institutions, Harbin 150081, People’s Republic of China; and Department of Gynecology, First Affiliated Hospital, Harbin Medical University, Harbin 150001, People’s Republic of China; and Depa...
متن کاملCTL Responses to a DNA Vaccine Encod-ing E7 Gene of Human Papillomavirus Type 16 from an Iranian Isolate
Background: Cervical cancer is the most prevalent tumor in developing countries and the second most frequent cancer among female population worldwide. Specific human papillomaviruses and, most notably, HPV types 16 and 18 are recognized as being caus-ally associated with cervical carcinomas. The early HPV type 16 genes, E6 and E7, di-rectly participate in the in vitro transformation of primary ...
متن کاملDetection of Human Papillomavirus DNA by PCR in Esophageal Squamous Cell Carcinoma from Turkmen Sahra, North-East of Iran
Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographical locations. In this study, neoplasms from Turkmen Sahra, a region in Golestan province in northeast part of Iran, with a high incidence of squamous cell carcinoma were analyzed for the presence of HPV DNA. Turkmen Sahra is located in the cancer...
متن کاملConstruction a DNA Vaccine Containing Human Papillomavirus Type 16 Early Genes as a Potential Vaccine for Cervical Cancer Prevention and Therapy
Background and Objectives: Some of the human papillomaviruses (HPVs) can infect genital tracts and are sometimes associated with anogenital tract cancers. HPVs induced cervical cancers through the expression of E6 and E7 genes by inactivating the tumor suppressor proteins. In this study, E6 and E7 genes were chosen in order to construct an expression vector which is able to express ...
متن کاملHuman papillomavirus prevalence among women with cervical intraepithelial neoplasia III and invasive cervical cancer from Goiânia, Brazil.
This study estimated the prevalence and distribution of human papillomavirus (HPV) types among women with cervical intraepithelial neoplasia (CIN) grade III and invasive cervical cancer from Goi s (Brazil Central Region). Seventy-four cases were analyzed and consisted of 18 CIN III, 48 squamous cell carcinomas, 4 adenocarcinomas, 1 adenosquamous carcinoma and 3 undifferentiated carcinomas. HPV-...
متن کامل